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Encyclopedia of Molecular Mechanisms of Disease
F LORIAN L ANG (Ed.)
Encyclopedia of Molecular
Mechanisms of Disease
With 646 Figures* and 213 Tables
*For color figures please see our Electronic Reference on www.springerlink.com
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Editor:
Prof. Dr. med. Florian Lang
Institute of Physiology
University of Tuebingen
Tuebingen, Germany
florian.lang@uni-tuebingen.de
A C.I.P. Catalog record for this book is available from the Library of Congress
ISBN: 978-3-540-67136-7
This publication is available also as:
Electronic publication under ISBN 978-3-540-29676-8 and
Print and electronic bundle under ISBN 978-3-540-33445-3
Library of Congress Control Number 2008930847
This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of
translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in other ways, and storage in data banks.
Duplication of this publication or parts thereof is only permitted under the provisions of the German Copyright Law of September 9, 1965, in
its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the
German Copyright Law.
© Springer-Verlag GmbH Berlin Heidelberg 2009
The use of registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names
are exempt from the relevant protective laws and regulations and therefore free for general use.
Product liability: The publishers cannot guarantee the accuracy of any information about the application of operative techniques and medications
contained in this book. In every individual case the user must check such information by consulting the relevant literature.
Springer is part of Springer Science+Business Media
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Printed on acid-free paper SPIN: 11 73 68 75 2109 543210
Preface
Pathophysiology describes mechanisms of disease and is thus at the interface between basic research and clinical
medicine. The aim of this comprehensive encyclopedia is to supply the reader with concise information on
molecular pathophysiology, a research area of breathtaking gain of knowledge. We trust that the book shall be a
valuable companion for both basic scientists exploring the clinical hallmarks of the diseases they are interested in,
and clinicians searching for insight into the molecular pathophysiology of their patients. The entries are structured
to allow rapid retrieval of the desired information. For more detailed reading, each entry is followed by key
references.
The editor is indebted to the section editors for their superb support in selecting the appropriate entries and choosing
the leading experts in the respective areas of research. The editor further wishes to express his appreciation to the
many brilliant authors who delivered outstanding state-of-the-art descriptions of pathophysiological mechanisms.
In addition, the book would not have come to reality without the dedicated, professional and creative support of
my secretaries Tanya Loch and Jasmin Bühringer and by several staff members of the Springer Publishing
house including Dr. Michaela Bilic, Jana Simniok, Hiltrud Wilbertz, Dr. Rolf Lange, and Dr. Thomas Mager.
F LORIAN L ANG , March 2008
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