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BIOPHOTONICS

Optical Science and Engineering

for the 21st Century

BIOPHOTONICS

Optical Science and Engineering

for the 21st Century

Edited by

Xun Shen

Institute of Biophysics

Chinese Academy of Sciences

Beijing, China

and

Roeland Van Wijk

Station Hombroich

International Institute of Biophysics

Neuss, Germany

^ Sprin g er

ISBN-10: 0-387-24995-8

ISBN-13: 978-0387-24995-7

elSBN: 0-387-24996-6

permission of the publisher (Springer Science-HBusiness Media, Inc., 233 Spring Street, New York,

NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in

connection with any form of information storage and retrieval, electronic adaptation, computer

software, or by similar or dissimilar methodology now known or hereafter developed is forbidden.

The use in this publication of trade names, trademarks, service marks and similar terms, even if they

are not identified as such, is not to be taken as an expression of opinion as to whether or not they are

subject to proprietary rights.

Printed in the United States of America

987654321

SPIN 11393429

springeronline.com

PREFACE

Biophotonics deals with interactions between photons and biological matter. It is an

exciting frontier that involves a fusion of photonics and biology. Biophotonics is the

science of generating and harnessing light (photons) to image, detect and manipulate

biological materials. It offers great hope for the early detection of diseases and for new

modalities of light-guided and light-activated therapies. It also provides powerful tools

for studying molecular events, such as gene expression, protein-protein interaction,

spatial and temporal distribution of the molecules of biological interest, and many

chemico-physical processes in living cells and living organisms. Fluorescence, scattering

and penetrating light are frequently used to detect and image the biological systems at

molecular, cellular and organismic levels. The light generated by metabolic processes in

living organisms also provides a good optical means to reflect the structure and function

of the living cells and organisms, which leads to a special aspect of biophotonics called

"Biophoton research". Either biophotonics or biophoton research creates many

opportunities for chemists, physicists, biologists, engineers, medical doctors and

heahhcare professionals. Also, educating biomedical personnel and new generations of

researchers in biophotonics is of the utmost importance to keep up with the increasing

worldwide demands.

On October 12-16 2003, scientists from 12 nations met in Beijing in order to present

and to discuss the most recent results in the interdisciplinary field of biophotonics and

biophoton research. Profound discussions were devoted to the new spectroscopic

techniques in microscopic imaging and optical tomography that allow determination of

the structures and functions in cells and tissues. Besides problems of basic research in

this field of biophotoiucs, various applications of these new optical technologies in

non-invasive or minimally invasive optical imaging, monitoring, and sensing of complex

systems such as tissues at the cellular level and cells at the subcellular level have been

presented. Scientists working in the particular field of biophoton research presented new

and exciting experimental results on spontaneous photon emission from living organisms.

They discussed the probable light sources within the cells, the possible coherence of the

photon field within the organism, and its bio-communicative aspects.

The field of biophotonics and biophoton research as covered in this book is an

important step forward in our understanding of the essence of biology, which is

composite and complex. Biology studies organisms: objects, which are complicated

Biophotonics-Optical Science and Engineering for the 21st Century - Xun Shen.pdf

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