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FLAVONOIDS
Chemistry, Biochemistry
and Applications
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FLAVONOIDS
Chemistry, Biochemistry
and Applications
Edited by
Øyvind M. Andersen
Kenneth R. Markham
Boca Raton London New York
A CRC title, part of the Taylor & Francis imprint, a member of the
Taylor & Francis Group, the academic division of T&F Informa plc.
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Published in 2006 by
CRC Press
Taylor & Francis Group
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Boca Raton, FL 33487-2742
© 2006 by Taylor & Francis Group, LLC
CRC Press is an imprint of Taylor & Francis Group
No claim to original U.S. Government works
Printed in the United States of America on acid-free paper
10987654321
International Standard Book Number-10: 0-8493-2021-6 (Hardcover)
International Standard Book Number-13: 978-0-8493-2021-7 (Hardcover)
Library of Congress Card Number 2005048626
This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with
permission, and sources are indicated. A wide variety of references are listed. Reasonable efforts have been made to publish
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or for the consequences of their use.
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Library of Congress Cataloging-in-Publication Data
Flavonoids : chemistry, biochemistry, and applications / edited by Øyvind M. Andersen and Kenneth R.
Markham.
p. cm.
Includes bibliographical references and index.
ISBN 0-8493-2021-6 (alk. paper)
1. Flavonoids. I. Andersen, Øyvind M. II. Markham, Kenneth R.
QP671.F52F53 2005
612’.01528--dc22
2005048626
Taylor & Francis Group
is the Academic Division of Informa plc.
Visit the Taylor & Francis Web site at
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Andersen and Markham / Flavonoids: Chemistry, Biochemistry, and Applications #2021_C000 Final Proof page 3 8.11.2005 9:11pm
Editors
Øyvind M. Andersen, a full professor of chemistry since 1993, has specialized in the chemistry
of natural compounds. Since 2002, he has been head of the Department of Chemistry,
University of Bergen, Norway. He received his Ph.D. degree in 1988
from the University of Bergen. He is author or coauthor of 100 journal
articles, seven book chapters, and five patents, and has supervised over
40 M.Sc. and Ph.D. students in the fields of anthocyanins and other
flavonoids. The activities of Dr. Andersen’s research group have led to
the establishment of several flavonoid-based companies. Most of his
research projects concentrate on structural elucidation of new com-
pounds, while others are methodology based and relate to NMR spec-
troscopy and various chromatographic techniques. Some of the projects
focus on anthocyanin properties with the objective of exploring their pharmaceutical poten-
tial and their use as colorants in food.
Kenneth R. Markham (Ken) has recently retired from his position as group leader and
distinguished scientist at Industrial Research Ltd., a New Zealand Crown Research Insti-
tute. Following completion of his B.Sc. and M.Sc. (Hons) at Victoria
University, Wellington, New Zealand, and his Ph.D. in chemistry
(University of Melbourne, Australia, 1963), he returned to Chemistry
Division, D.S.I.R., in Lower Hutt, New Zealand, to work on xanthone
chemistry. His interest in flavonoids began during a 2-year postdoctoral
with Professor Tom Mabry at the University of Texas at Austin (1965–
1967). The coauthored book The Systematic Identification of Flavo-
noids resulted from this interaction. On his return to New Zealand,
Dr. Markham established and led the ‘‘Natural Products’’ section,
predominantly devoted to the study of flavonoids with particular em-
phasis on the chemotaxonomy of New Zealand bryophytes, ferns, and gymnosperms. This
work was carried out in conjunction with both local botanists and colleagues at the University
of Saarbrucken (Professors Zinsmeister, Mues, and Geiger). In 1979, he worked as a visiting
scientist with Professor Jeffrey Harborne at the University of Reading. This again resulted in
the publication of a popular book, Techniques of Flavonoid Identification. Dr. Markham’s
flavonoid research continued at Industrial Research Ltd. and has led him into studies as
diverse as plant chemotaxonomy, plant evolution, plant UV protection, historical Antarctic
ozone levels, propolis and bee pollen bioactives, G.E. modification of flower color, and
subcellular chemistry, to name but a few. His work has been reported in some 280 publica-
tions, including 18 invited chapters and two books, and has been recognized over the years
through awards such as the Chemical Society’s Easterfield Medal, Fellowship of the Royal
Society of New Zealand, a Ministerial Award for Excellence in Scientific Research, and the
1999 Pergamon Phytochemical Prize.
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