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Science Magazine August 22 2008
22 August 2008
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CONTENTS
Volume 321, Issue 5892
COVER
Using sunlight to rearrange the chemical
bonds of water into hydrogen and oxygen, as
in photosynthesis, would constitute a practical
way to store solar energy as a fuel. Such an
energy source will depend on new catalysts
that promote this fuel-forming reaction
cheaply and efficiently. See
page 1072.
Photo illustration: Paul Montie
(images:
iStockphoto.com;
Getty Images)
DEPARTMENTS
1015
Science
Online
1016
This Week in
Science
1020
Editors’ Choice
1022
Contact
Science
1023
Random Samples
1025
Newsmakers
1103
New Products
1104
Science
Careers
EDITORIAL
1019
Science and Security, Again
by Donald Kennedy
NEWS OF THE WEEK
FBI Discusses Microbial Forensics—but Key
1026
LETTERS
An Editor’s Checklist
R. W. Guillery
1039
Questions Remain Unanswered
Six Anthrax Science Questions the FBI Has Yet to Answer
Pumping Up the Tibetan Plateau From the
1028
High-Profile Journals Not Worth the Trouble
J. L. Rosenbaum
Taking Responsibility for Scientific Discourse
S. D. Friedman
The Carrageenan Diet: Not Recommended
J. K. Tobacman
et al.
CORRECTIONS AND CLARIFICATIONS
Far Pacific Ocean
>> Review
p. 1054
‘Simple’ Animal’s Genome Proves Unexpectedly
1028
Complex
SCIENCESCOPE
1040
1029
BOOKS
ET AL.
Just One Child
Science and Policy in Deng’s China
New Regulation Would Lessen Influence of
1030
Fish and Wildlife Experts
Departments Scramble to Find Math Education
1042
S. Greenhalgh, reviewed by E. A. Mueggler
Fatal Misconception
The Struggle to Control World
1031
Faculty
1043
Population
M. Connelly, reviewed by J. C. Caldwell
NEWS FOCUS
Turbulent Times for Climate Model
1032
POLICY FORUM
Toward a Global Biodiversity Observing System
1042
>>
Science
Podcast
Shielding a Buddhist Shrine From the Howling
1044
1035
R. J. Scholes
et al.
Desert Sands
Can High-Speed Tests Sort Out Which Nanomaterials
1036
PERSPECTIVES
The Unseen Mind
Are Safe?
1046
T. D. Wilson and Y. Bar-Anan
>> Report
p. 1100
Stars in the Making
1047
P. J. Armitage
>> Report
p. 1060
How Now, Brown Fat?
1048
M. A. Lazar
Soluble Allotropes of Main-Group Elements
1050
C. A. Dyker and G. Bertrand
>> Report
p. 1069
A Matter of Timing
1051
B. E. Lyon, A. S. Chaine, D. W. Winkler
Using Tobacco to Treat Cancer
1052
C. J. Arntzen
1032
CONTENTS
continued
>>
www.sciencemag.org
SCIENCE
VOL 321 22 AUGUST 2008
1009
CONTENTS
SCIENCE EXPRESS
www.sciencexpress.org
PHYSICS
Quantum Communication with Zero-Capacity Channels
G. Smith and J. Yard
Two quantum communication channels, each of which is so noisy that it has
zero-capacity to independently transmit information, can do so when used together.
10.1126/science.1162242
DEVELOPMENTAL BIOLOGY
Chemokine Signaling Controls Endodermal Migration During Zebrafish
Gastrulation
S. Nair and T. F. Schilling
During zebrafish gastrulation, chemokines are required for integrin-dependent
adhesion of endodermal cells to mesoderm, a role distinct from their action as
chemoattractants.
10.1126/science.1160038
CELL BIOLOGY
High-Quality Binary Protein Interaction Map of the Yeast Interactome
Network
H. Yu
et al.
Comparison of existing methods for mapping protein-protein interactions in yeast
cells shows that the high-throughput approaches are complementary to one another.
10.1126/science.1158684
PHYSICS
Coupled Superconducting and Magnetic Order in CeCoIn
5
M. Kenzelmann
et al.
Unlike other superconductors, magnetic ordering coexists with and is stabilized by
superconductivity in the exotic superconductor CeCoIn.
10.1126/science.1161818
1040
and
Tyrannosaurus rex
Revealed by Mass Spectrometry”
P. A. Pevzner, S. Kim, J. Ng
full text at
www.sciencemag.org/cgi/content/full/321/5892/1040b
Response to Comment on “Protein Sequences
from Mastodon and
Tyrannosaurus rex
Revealed
by Mass Spectrometry”
J. M. Asara, M. H. Schweitzer, L. C. Cantley, J. S. Cottrell
full text at
www.sciencemag.org/cgi/content/full/321/5892/1040c
BREVIA
ATMOSPHERIC SCIENCE
N
2
O
5
Oxidizes Chloride to Cl
2
in Acidic
1059
Atmospheric Aerosol
J. M. Roberts
et al.
Laboratory studies affirm that the oxidation of chloride ions in
aerosols by N
2
O
5
is a significant source of chlorine in the troposphere,
a major reactant that helps form ozone.
REPORTS
ASTRONOMY
Star Formation Around Supermassive Black Holes
1060
REVIEW
GEOLOGY
The Geological Evolution of the Tibetan Plateau
I. A. Bonnell and W. K. M. Rice
Simulations show that the disruption of a molecular cloud by a
black hole can lead to the formation of nearby stars with eccentric
orbits, explaining observations in our Galaxy.
>> Perspectiv
e p. 1047
PHYSICS
Quantum Gas of Deeply Bound Ground State
1054
L. H. Royden, B. C. Burchfiel, R. D. van der Hilst
>> News story
p. 1028
1062
Molecules
J. G. Danzl
et al.
A coherent Raman pumping scheme cools cesium molecules
to a state with minimal rotational energy, needed for producing
cold molecular Bose-Einstein condensates.
MATERIALS SCIENCE
Observation of Atomic Diffusion at Twin-Modified
1066
Grain Boundaries in Copper
K.-C. Chen, W.-W. Wu, C.-N. Liao, L.-J. Chen, K. N. Tu
The presence of twinned grains at grain boundaries reduces
current-induced diffusion of atoms in small copper wires,
which can produce voids or even breaks.
1052
CONTENTS
continued
>>
www.sciencemag.org
SCIENCE
VOL 321 22 AUGUST 2008
1011
TECHNICAL COMMENT ABSTRACTS
PALEONTOLOGY
Comment on “Protein Sequences from Mastodon
CONTENTS
REPORTS
CONTINUED...
CHEMISTRY
A Stable Silicon(0) Compound with a Si=Si
1069
MOLECULAR BIOLOGY
Heterochromatin Integrity Affects Chromosome
1088
Double Bond
Y. Wang
et al.
Carbene ligands stabilize diatomic silicon without oxidizing it,
an unusual motif for a light element.
>> Perspective
p. 1050
CHEMISTRY
In Situ Formation of an Oxygen-Evolving Catalyst in
1072
Reorganization After Centromere Dysfunction
K. Ishii
et al.
When the centromere is removed from a yeast chromosome, a new
one forms near the end of the chromosome, over a cluster of poorly
expressed genes.
NEUROSCIENCE
Grueneberg Ganglion Cells Mediate Alarm
1092
Neutral Water Containing Phosphate and Co
2+
M. W. Kanan and D. G. Nocera
A catalyst that precipitates in situ when cobalt ions are reduced
in a phosphate buffer efficiently forms oxygen from water needed
for electrochemical applications.
ATMOSPHERIC SCIENCE
The Global Atmospheric Circulation on Moist
Pheromone Detection in Mice
J. Brechbühl, M. Klaey, M.-C. Broillet
A mysterious ganglion at the tip of the nose is an olfactory subsystem
that senses alarm pheromones in mice.
CELL BIOLOGY
Control of the Reversibility of Cellular Quiescence
1095
1075
by the Transcriptional Repressor HES1
L. Sang, H. A. Coller, J. M. Roberts
For quiescent cells to periodically divide and then rest, a member
of the Notch signaling pathway HES1 must be present; this protein
is also activated in some tumors.
PSYCHOLOGY
Automatic Mental Associations Predict Future
Isentropes
O. Pauluis, A. Czaja, R. Korty
An analysis of global atmospheric circulation from 1970 to 2004
shows that more mid-latitude air rose into the upper troposphere
than current models would suggest.
MICROBIOLOGY
Targeting QseC Signaling and Virulence for
1100
1078
Choices of Undecided Decision-Makers
S. Galdi, L. Arcuri, B. Gawronski
Unexpectedly, consciously expressed voting choices predict later
unconscious preferences, showing that unconscious and conscious
cognition is a two-way street.
>> Perspective
p. 1046;
Science
Podcast
Antibiotic Development
D. A. Rasko
et al.
A small, nontoxic antibiotic candidate interferes with bacterial
detection of the host and inhibits infection, in a therapeutic
approach that may avoid development of resistance.
>>
Science
Podcast
IMMUNOLOGY
Variability and Robustness in T Cell Activation from
1081
Regulated Heterogeneity in Protein Levels
O. Feinerman
et al.
Variations in component levels of the antigen-induced signaling
pathway affect the final response of activated immune cells,
conferring flexibility on the system.
VIROLOGY
Adenovirus Small e1a Alters Global Patterns of
1084
Histone Modification
G. A. Horwitz
et al.
Epigenetic Reprogramming by Adenovirus e1a
1086
R. Ferrari
et al.
Upon infection, an adenovirus protein causes global epigenetic
changes in the host that repress antiviral responses and
differentiation and activate cell-cycle genes.
1086
SCIENCE (ISSN 0036-8075) is published weekly on Friday, except the last week in December, by the American Association
for the Advancement of Science, 1200 New York Avenue, NW, Washington, DC 20005.
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CONTENTS
continued
>>
www.sciencemag.org
SCIENCE
VOL 321 22 AUGUST 2008
1013
ONLINE
Head-turner.
NOW
www.sciencenow.org
HIGHLIGHTS FROM OUR DAILY NEWS COVERAGE
Oh, Brad, You’re So . . . Symmetrical
Balanced bodies are more attractive, study shows.
Ancient Beavers Take Silver in Log-Chomping Olympics
Fossilized logs peg today’s beavers as the true lumberjacks.
Sniffing for Mr. Right
Birth control could change a woman’s sense of the perfect man.
A better retirement for scientists.
CAREERS
www.sciencecareers.org/career_development
FREE CAREER RESOURCES FOR SCIENTISTS
Measuring responses to mechanical force
.
Tooling Up: Defying Gravity
D. Jensen
To succeed in science—especially in industry—intellectual
brilliance may be necessary, but it’s not sufficient.
A Comfortable Retirement
G. Sinha
European countries are working to improve pensions for mobile
scientists.
Science
Careers Poll Results: A Realistic Readership
J. Austin
Grad students and postdocs are guardedly optimistic about their
career prospects.
From the Archives: Choosing a Thesis Lab
S. Brass
For M.D./Ph.D. students, the thesis-lab choice poses special
challenges.
SIGNALING
www.sciencesignaling.org
THE SIGNAL TRANSDUCTION KNOWLEDGE ENVIRONMENT
PROTOCOL: Application of Fluorescence Resonance Energy
Transfer and Magnetic Twisting Cytometry to Quantify
Mechano-Chemical Signaling Activities in a Living Cell
S. Na and N. Wang
Get detailed instructions for delivering biologically relevant
mechanical stress to individual cells and observing the intracellular
signaling activities that ensue.
PRESENTATION: Defining Drug Targets in Yeast
Haploinsufficiency Screens—Application to Human
Translational Pharmacology
M. Roberge
Identifying targets of drugs in yeast using genome-wide
drug-induced haploinsufficiency is a viable approach to predicting
drug targets in humans.
PODCAST
www.sciencemag.org/multimedia/podcast
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Science
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SCIENCE
VOL 321 22 AUGUST 2008
1015
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