Celiac disease, also known as gluten intolerance, is a genetic disorder.
Symptoms of celiac disease can range from the classic features, such as diarrhea, weight loss, and malnutrition, to latent symptoms such as isolated nutrient deficiencies but no gastrointestinal symptoms.
The disease mostly affects people of European (especially Northern European) descent, but recent studies show that it also affects Hispanic, Black and Asian populations as well.
Those affected suffer damage to the villi (shortening and villous flattening) in their intestines when they eat specific food-grain antigens (toxic amino acid sequences) that are found in wheat, rye, barley and oats.
Because of the broad range of symptoms celiac disease presents, it can be difficult to diagnose.
The symptoms can range from mild weakness, bone pain, and aphthous stomatitis to chronic diarrhea, abdominal bloating, and progressive weight loss.
If a person with the disorder continues to eat gluten, studies have shown that he or she will increase their chances of gastrointestinal cancer by a factor of 40 to 100 times that of the normal population.
Further, gastrointestinal carcinoma or lymphoma develops in up to 15 percent of patients with untreated or refractory celiac disease. It is therefore imperative that the disease is quickly and properly diagnosed so it can be treated as soon as possible.
It is very important that doctors understand just how many people have this disease so that routine testing for it is done to bring the diagnosis rate in line with the diseases epidemiology.
Testing is fairly simple and involves screening the patients blood and/or doing a biopsy on of the intestines , which is still the standard for a formal diagnosis.
The only acceptable treatment for celiac disease is strict adherence to a 100% gluten-free diet for life. An adherence to a gluten-free diet can prevent almost all complications caused by the disease.
A gluten-free diet means avoiding all products that contain wheat, rye and barley, or any of their derivatives.
celiac disease – Celiakia
disease – choroba
gluten-free diet – dieta bezglutenowa
a genetic disorder – choroba genetyczna -
gluten intolerance – nietolerancja glutenu
symptoms – objawy
gastrointestinal – przewód pokarmowy
gastrointestinal symptoms – objawy żołądkowo-jelitowe(przewodu pokarmowego)
diarrhea – biegunka
weight loss – utrata masy ciała
malnutrition - niedożywienie
latent symptoms - objawy utajone
isolated nutrient deficiencies - izolowane niedobory substancji odżywczych
recent studies - ostatnie badania
suffer damage to - doznać obrażeń
the villi - kosmki
shortening and villous flattening - skrócenie i spłaszczenie kosmków
intestines - jelita
grain - ziarna
antigens - antygeny
toxic amino acid sequences - toksycznych sekwencji aminokwasowych
wheat - przenica
rye - żyto
barley - jęczmień
oats - owies
the broad range of symptoms - szeroki zakres objawów
difficult to diagnose - trudne do zdiagnozowania
range - w zakresie
mild weakness - łagodne osłabienie
bone pain - ból kości
aphthous stomatitis - aftowe zapalenie jamy ustnej
chronic diarrhea - przewlekła biegunka
abdominal bloating - wzdęcia
progressive weight loss - stopniową utratę wagi
will increase their chances - zwiększy ich szanse
gastrointestinal cancer - rak przewodu pokarmowego
lymphoma - chłoniak
patients - pacjenci
untreated - nieleczony
refractory - oporny, odporny
routine testing - rutynowe badania
diseases epidemiology - epidemiologia chorób
diagnosis - diagnoza
involves - obejmuje
screening the patients blood - badania krwi pacjentów
biopsy - biopsja
complications - komplikacje
avoiding - unikając
derivatives - pochodne
Nisa